Insitec: on-line particle size analysis for automated milling control
Uploaded on 18 Mar 2010
This video shows how Malvern Instruments Insitec particle size analyzer is used to control and automate a milling process. Real-time measurement of particle size distribution (PSD) is used as a feedback for controlling raw material feed rate.
Protein mobility measurements on the Zetasizer Nano ZSP
Published on 28 Sep 2012
The launch of the Zetasizer Nano ZSP in 2012 was accompanied by additions to the Zetasizer software, that were specifically designed to make protein mobility measurements more simple. These included a protein mobility standard operating procedure, and tools for calculating protein charge. This video describes how the Zetasizer Nano ZSP can be used to make a protein mobility measurement, and includes details of a new type of sample introduction, the diffusion barrier technique.
Analysis of particle shape, size & chemical identity - Morphologi G3-ID
Published on 1 Oct 2012
Malvern's particle shape analyzer. A brief introduction to the Morphologi G3-ID, a unique new instrument for measurement and analysis of particle shape, particle size, and chemical identity.
Creating a spectral library on the Morphologi G3-ID
Published on 10 Oct 2012
This short video shows you how easy it is to add reference spectra into a library for the Morphologi G3-ID instrument.
Microrheology measurements on the Zetasizer Nano ZSP
Published on 15 Oct 2012
The launch of the Zetasizer Nano ZSP in was accompanied by additions to the Zetasizer software, that saw the introduction of a new microrheology measurement type. Dynamic light scattering microrheology is an optical technique that involves tracking the motion of dispersed tracer particles of known size, in a fluid, to determine the rheological properties of the sample. The update to the Zetasizer software also includes a microrheology standard operating procedure. http://www.malvern.com/en/products/me...This video describes how the Zetasizer Nano ZSP can be used to make a microrheology measurement, and the subsequent calculation of viscoelastic moduli G' and G'' and the complex viscosity of low viscosity and weakly structured complex fluids.
High-throughput protein analysis with the Zetasizer APS
Published on 14 Feb 2014
The Zetasizer APS (or Automated Plate Sampler) is a robust, simple to operate Dynamic Light Scattering (DLS) instrument, perfect for protein characterization, including the detection of aggregates in protein solutions, optimization of storage conditions to avoid aggregation, and screening of small molecule libraries for aggregated compounds that could act as non-specific inhibitors. As part of a range of class-leading products from Malvern Instruments, the performance in terms of sensitivity, accuracy and repeatability is identical to the batch capabilities of the Zetasizer uV and Zetasizer Nano, but with the advantage of full automation. This means that reliable size measurements and thermal trends of proteins can be made unattended, improving productivity.
Protein characterization with the Zetasizer MicroV batch & flow mode
Published on 14 Feb 2014
The Zetasizer µV (MicroV) is a dual purpose light scattering instrument designed specifically for protein characterization, including protein aggregation. Firstly, it is a highly sensitive cuvette based dynamic light scattering instrument with the same great performance as the market leading Zetasizer Nano. Secondly, by simply changing the cell, it becomes an absolute molecular weight and size detector that can be added to any Size Exclusion Chromatography system (such as the Viscotek TDAmax).
Malvern Archimedes - Particle Count using Resonant Mass Measurement
Published on 9 May 2014
Malvern Instruments' Archimedes is a new, highly innovative instrument which uses the technique of resonant mass measurement to detect and accurately count particles (particle concentration) in the size range 50nm - 5µm, and reliably measure their buoyant mass, dry mass and size. Particularly useful for the detection and protein characterization, including protein aggregates in formulation or buffer,
Archimedes is also able to distinguish between proteinaceous material and contaminants such as silicone oil by means of comparing their relative resonant frequencies and buoyant masses.
Automated particle size, shape & chemical identity measurement with Morphologi G3-ID
Published on 26 Aug 2014
The Morphologi G3-ID for automated measurement of particle size, particle shape and chemical identity.
http://bit.ly/VLyvMH - The Morphologi G3-ID provides a unique capability, combining automated static imaging features of the Morphologi G3 with chemical identification of individual particles using Raman spectroscopy to enable the measurement of component specific particle size and particle shape distributions. This fully automated instrument is designed to allow both particle characterization scientists with limited spectroscopy experience and more experienced spectroscopists to get an in-depth understanding of their particulate samples.
Principles of isothermal titration calorimetry (ITC)
Published on 22 Jul 2014
Introduction to the principles of isothermal titration calorimetry & MicroCal's ITC microcalorimeter. View the Malvern Range of ITC solutions.
Laser diffraction particle size analyzer - Mastersizer 3000
Published on 13 Mar 2013
The Mastersizer 3000 laser diffraction particle size analyzer delivers rapid, accurate particle size distributions for both wet and dry dispersions with the minimum of effort. Measuring over the nanometer to millimeter particle size ranges, it packs exceptional performance into the smallest of footprints, bringing operator-independent measurements that every user can rely on.
MicroCal PEAQ-ITC - advanced Isothermal Titration Calorimetry
Published on 16 Apr 2015
MicroCal PEAQ-ITC, the most advanced Isothermal Titration Calorimetry system from Malvern Instruments, offers high quality data, ease of use, and exceptional sensitivity.
The Malvern Mastersizer 3000 Particle Size Analyzer
Published on 24 Feb 2016
Julie Chen from Malvern Instruments shows us Malvern's new Mastersizer 3000 particle size analyzer. She outlines upgrades from the Mastersizer 2000 and demonstrates some of the key features and operation of the instrument.
Simple, versatile dynamic light scattering system - Zetasizer Nano
Published on 14 Feb 2014
The Zetasizer Nano is the world's most widely used dymanic laser light scattering system, for measuring size, zeta potential and molecular weight. Applications range from characterizing high concentration colloids and nanoparticles, through to measurement of proteins and macromolecules in their native state, requiring as little as 12 microlitres of sample. The Zetasizer Nano can be used for the comprehensive characterization of proteins, colloids and nanoparticles, and is simple to use, highly sensitive, versatile and fast! This videos shows how quickly and easily a measurement can be made on the Zetasizer Nano.
The Malvern Zetasizer Nano surface zeta potential cell
Published on 2 May 2012
The surface zeta potential cell is a new accessory for the Malvern Zetasizer Nano. It allows the measurement of the zeta potential of flat surfaces. This video demonstrates how to use the cell and make a measurement using the Zetasizer software.
Principles of Differential Scanning Calorimetry (DSC)
Published on 2 Nov 2015
Learn about the principles of Differential Scanning Calorimetry (DSC).
Differential Scanning Calorimetry (DSC) is a technique for understanding the stability of proteins and other biomolecules. It has wide application in protein engineering, rational drug design and biopharmaceutical production, where developing stable proteins is a critical goal.
MicroCal DSC microcalorimeters are powerful analytical tools for characterizing the stability of proteins and other biomolecules, requiring minimal assay development, no labelling or immobilization. The automation and high sensitivity afforded by MicroCal VP-Capillary DSC systems permits screening of large numbers of samples at low concentrations minimizing the consumption of valuable samples with little hands-on effort.
Mastersizer 3000: Smarter Laser Diffraction Particle Sizing
Published on 1 Sep 2014
The Mastersizer 3000 is the latest generation of the world’s most popular particle sizing instrument.
The Mastersizer 3000 laser diffraction particle size analyzer delivers rapid, accurate particle size distributions for both wet and dry dispersions with the minimum of effort. Measuring over the nanometer to millimeter particle size ranges, it packs exceptional performance into the smallest of footprints, bringing operator-independent measurements that every user can rely on.